REF MISC
MEN2: RET Gene Sequencing
Synonyms:
Multiple Endocrine Neoplasia
MEN2
RET proto-oncogene
Performing Lab:
Referral Laboratory
Required Patient Info:
FORMS: Molecular Genetics: Inherited Cancer Syndromes Patient Information (T519) must be sent with specimen.
Container Type:
Lavender top (EDTA) tube or Yellow-top (ACD)
Specimen Type:
Whole blood
Preferred Volume:
3 mL
Alternate Specimens:
Any anticoagulant (no GEL)
Minimum Volume:
1 mL
Specimen Processing:
Send specimen in original tube.
Store and Transport:
Room temperature (Preferred)
Stability:
Specimen preferred to arrive at testing lab within 96 hours.
Unacceptable Condition:
All specimens will be evaluated by Mayo Clinic Laboratories for test suitability
CPT Codes:
81406
Method:
Next-generation sequencing is used to test for the presence of a mutation in all coding regions and intron/exon boundaries of the RET gene. Sanger sequencing is used to confirm alterations detected by next-generation sequencing when appropriate