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As we move into fall, you might be feeling at the top of your game—you’ve made it a priority to exercise regularly, eat a balanced diet, and get stress under control. Plus, you’re one of those people who just doesn’t get sick very often. You might be wondering: Can I skip getting a flu shot?

First, it was the checkbook.

Sue Jameson, 84, from Chillicothe, Missouri, was meticulous in balancing the family finances. One day in 2020, her husband, Douglas, noticed she hadn’t made any entries for several months.

He then started to notice Sue’s recurring memory issues, which came with a scary moment when she fell asleep while driving. She drove off the road but regained consciousness before safely driving back home. While relieved, her family had growing concerns.