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Fabian Hardy has been healthy all his life: he served in the military, he consistently ate well – including fruits and vegetables – exercised, saw his doctor regularly and had a clean bill of health.

For three years, Linda Braxdale endured throbbing pain in her lower back and down her left leg. The pain and frustration often left her feeling helpless and defeated—and reduced to tears.

For three decades, breathing troubles followed James Seymore as he and his wife moved from one place to another. In 1980, he received his first diagnosis of pulmonary sarcoidosis in Wyoming. The inflammatory condition can cause shortness of breath, coughing, fatigue, and joint pain. His first bout resolved after a course of steroids, but it returned seven years later after the Seymores moved to Oregon.