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While the mortality rate for breast cancer in the U.S. has significantly declined from its peak in 1989, incidence among younger women has steadily increased each year since 2001, according to the American Cancer Society.

For three decades, breathing troubles followed James Seymore as he and his wife moved from one place to another. In 1980, he received his first diagnosis of pulmonary sarcoidosis in Wyoming. The inflammatory condition can cause shortness of breath, coughing, fatigue, and joint pain. His first bout resolved after a course of steroids, but it returned seven years later after the Seymores moved to Oregon.

Shanon Wolfe's varicose vein troubles were more than cosmetic. Although her legs didn’t hurt at the end of the day, more and more often they felt heavy and tired. It began interfering with her kickboxing.