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Five years ago, 66-year-old Diane Hicks had a health scare that turned out to be a turning point for her entire life. She learned she needed to seriously consider a kidney transplant to improve her overall health and life expectancy.

While chemotherapy, radiation, and surgeries are common for most cancer treatments, immunotherapy is continuing to allow some patients to forgo these often harsh and invasive methods altogether.

More than 10 years after his diagnosis, he’s helping other people with the same rare cancer to hold on to hope.

As Sallie Wickens boarded the LifeFlight helicopter in Climax Springs, Missouri, in June 2012, she had no idea it would be the last leg of a journey that started when she was 5 years old.