Medpage Today: Tricuspid Clip Might Work for More Patients Than Thought
Tricuspid transcatheter edge-to-edge repair (T-TEER) performed better than anticipated in patients expected to have only a modest benefit due to more complex anatomy, the TRILUMINATE trial showed.
After receiving the investigational TriClip device to hold the leaflets together, most patients enrolled in the single-arm portion of the trial as a result of their complex anatomies -- presumed to preclude a reduction in tricuspid regurgitation (TR) to moderate or less -- actually achieved that grade of regurgitation.
In a separate analysis of the initial 350 randomized patients diving deeper into the quality of life findings, Suzanne Arnold, MD, MHA, of Saint Luke's Mid America Heart Institute and the University of Missouri-Kansas City, reported a number needed to treat of 3.5 for one additional patient to be alive and well at 12 months.
"Exploratory analyses suggested that much of the health status benefit of T-TEER could be explained by TR reduction and that improvement in health status after T-TEER was strongly correlated with reduced 1-year mortality and heart failure hospitalization," her group wrote in a paper simultaneously released in the Journal of the American College of Cardiology.
Read the full Medpage Today article: Tricuspid Clip Might Work for More Patients Than Thought
