Questions About Your Risk for Hereditary Breast Cancer

Section 1

Have you or any relatives had either of the following?

A breast cancer diagnosis at age 50 or younger

Two cancers diagnosed in the same person, with one being breast cancer

Section 2

Seeing clusters of certain types of cancer in a family may raise concern for a hereditary breast cancer.

The next few questions will check for these clusters. Only consider cancers that occur in people who are on the same side of the family, either your mother's or father's side separately.

This means relatives who are all related to each other by blood, including yourself.

Is there a clustering of two people on the same side of the family, where one relative had breast cancer and the other relative had one of the following (especially if one was diagnosed at or under age 50). If yes, check the relevant boxes below.

Breast cancer

Colon or rectal cancer

Thyroid cancer

Sarcoma

Stomach cancer

Uterine (endometrial) cancer

Prostate cancer

Leukemia

Brain tumor

Are there three or more people on the same side of the family with the same cancer type listed below? If yes, check the relevant boxes below.

Breast cancer

Uterine (endometrial) cancer

Diffuse gastric (stomach) cancer

Colon or rectal cancer

Thyroid cancer

Brain tumor

Sarcoma

Leukemia

Section 3

Other non-cancerous growths can sometimes be seen with inherited breast cancer syndromes.

Do you or your health care provider have concerns that you or your relatives have any of the following non-cancerous growths?

Examples of non-cancerous growths include thyroid nodules/adenomas/goiters, gastrointestinal polyps, ganglioneuromas, rare skin findings such as trichilemmoma, oral papillomatosis, and facial papules, keratoses on hands/feet; or a very large head size.

Yes

Next steps

If you have checked any of the boxes above and/or said "yes", a genetics evaluation is recommended for you. Call the Saint Luke’s High-Risk Breast Clinic at 816-932-5332.

If you have not, a genetics evaluation is not recommended for you at this time.

Disclaimer
Criteria reflect national guidelines for genetic counseling referral for inherited breast cancer syndromes but does not assess risk for other cancer syndromes.

References
National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 1.2022. www.nccn.org.
USPSTF Statement: Risk Assessment, Genetic Counseling, and Genetic Testing for BRCARelated Cancer. JAMA. 2019;322(7):652-665

Copyright
2022 Informed Medical Decisions, Inc. (dba InformedDNA®)

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