AFP NTD
AFP Open Spina Bifida Maternal Serum Screen (only NTD marker)
EPIC Test Procedure Code: LAB3342
1. THIS TEST IS ONLY PERFORMED ON PATIENTS WITH GESTATION AGES BETWEEN 15.0 - 23.9 WEEKS.
2. Specimens must be collected before amniocentesis.
Patient information may be provided to the laboratory using the Request for Maternal Prenatal Screening
form 0900:
THE FOLLOWING INFORMATION IS REQUIRED FOR PROCESSING:
1. Gestational Age
2. Date on which the patient was the stated gestational age
3. How gestational age was determined (LMP, EDD, US)
4. Patient's weight
5. Patient's date of birth
6. Patient's race (white, black, other)
7. Insulin-dependent diabetic status
8. Indicate relevant patient history (e.g. prior neural tube defects, Down syndrome, ultrasound anomalies, or previous maternal serum screening specimen during this pregnancy).
Serum
Send specimen in the original tube. Pour off is not advised.
Frozen - 14 days
Refrigerated - 14 days
Room temperature - 7 days
Specimens that are grossly hemolyzed or grossly lipemic will be rejected.
82105 - AFP Open Spina Bifida (EAP 30021006)
Please refer to the performing lab report for applicable reference ranges
This is a screening test for open neural tube defects. It detects 80% of open spina bifida and 90% of anencephaly. This test does not provide screening for Down syndrome or trisomy 18.