AFP NTD

AFP Open Spina Bifida Maternal Serum Screen (only NTD marker)

EPIC Test Procedure Code: LAB3342

Synonyms:
Neural Tube Defect
AFP Only
Performing Lab:
Referral Laboratory
Patient Preparation:

1. THIS TEST IS ONLY PERFORMED ON PATIENTS WITH GESTATION AGES BETWEEN 15.0 - 23.9 WEEKS.
2. Specimens must be collected before amniocentesis.

Required Patient Info:

Patient information may be provided to the laboratory using the Request for Maternal Prenatal Screening
form 0900:

THE FOLLOWING INFORMATION IS REQUIRED FOR PROCESSING:

1. Gestational Age
2. Date on which the patient was the stated gestational age
3. How gestational age was determined (LMP, EDD, US)
4. Patient's weight
5. Patient's date of birth
6. Patient's race (white, black, other)
7. Insulin-dependent diabetic status
8. Indicate relevant patient history (e.g. prior neural tube defects, Down syndrome, ultrasound anomalies, or previous maternal serum screening specimen during this pregnancy).

Container Type:
Serum gel tube
Specimen Type:

Serum

Preferred Volume:
3 mL
Minimum Volume:
0.5 mL
Specimen Processing:

Send specimen in the original tube. Pour off is not advised.

Store and Transport:
Room Temperature
Stability:

Frozen - 14 days
Refrigerated - 14 days
Room temperature - 7 days

Unacceptable Condition:

Specimens that are grossly hemolyzed or grossly lipemic will be rejected.

CPT Codes:

82105 - AFP Open Spina Bifida (EAP 30021006)

Method:
Chemiluminescent immunoassay
Reference Ranges:

Please refer to the performing lab report for applicable reference ranges

Notes:

This is a screening test for open neural tube defects. It detects 80% of open spina bifida and 90% of anencephaly. This test does not provide screening for Down syndrome or trisomy 18.

Lab Personnel

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