REF MISC

EGFR Mutation Tumor Analysis

Synonyms:
T790M
Performing Lab:
Referral Laboratory
Specimen Type:

Lung tumor only in one of the following:

Tissue Block:
Formalin-fixed, paraffin-embedded.  Tissue should be well-fixed in formalin.  Ship at room temperature.

Paraffin-Embedded Tissue Slides:
Send all slides (5 minimum) within 5 - 7 days of cutting. Pre-cut slides from paraffin block in 7 micron sections.
Use non-charged, non-coated slides.
Ship at room temperature.

Fresh Snap Frozen Biopsy:
Fresh tissue should be snap frozen and stored at - 20 °C.
Ship frozen.

Plasma:
4 mL of EDTA plasma frozen (2 mL minimum). Plasma must be separated and frozen within 4 hours of collection. Send frozen. Must submit the patient's diagnosis (or ICD10 code) or testing will be delayed.

Collection Procedure:

For tissue samples only:

1. Complete the Integrated Oncology request form, mark as insurance bill and send a copy of the facesheet. Include diagnosis code, physician and npi number.
2. Provide a copy of the original pathology report.
3. Label the specimen with the patient name and ID number. Place the samples inside a specimen transport bag.
4. Use small Integrated Oncology boxes and Fed Ex air bills to send directly to Integrated Oncology, Los Angeles.

Unacceptable Condition:

Tumor sources other than lung are not acceptable.

CPT Codes:

81235

Lab Personnel

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