REF MISC
Multiple Myeloma Minimal Residual Disease by Flow Cytometry, Bone Marrow
Synonyms:
Multiple Myeloma MRD
Myeloma MRD
Plasma cell MRD
Performing Lab:
Referral Laboratory
Container Type:
Lavender top (EDTA) tube or ACD
Specimen Type:
Bone Marrow
Preferred Volume:
4 mL
Minimum Volume:
2 mL
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability
Specimen Processing:
It is recommended that specimens arrive within 48 hours of collection. Collect and package specimen as close to
shipping time as possible.
Store and Transport:
Room Temperature
Stability:
Room Temperature: 72 hours
Refrigerated: 72 hours
Unacceptable Condition:
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.
CPT Codes:
88184-Flow Cytometry; first cell surface, cytoplasmic or nuclear marker
88185 x 9-Flow Cytometry; additional cell surface, cytoplasmic or nuclear marker
88188-Flow Cytometry Interpretation, 9 to 15 Markers
Method:
Immunophenotyping for Minimal Residual Disease (MRD)
Reference Ranges:
Clinical Significance:
Useful For: Detecting low level (minimal residual disease) myeloma cells after therapy.
Highlights:
This is a high-sensitivity flow cytometry test for detection of minimal residual myeloma cells, post treatment
It uses adopted EuroFlow guidelines and Cytognos software
It has a sensitivity of 10(-5) or better, depending on the antigenic profile of abnormal plasma cells
Highlights:
This is a high-sensitivity flow cytometry test for detection of minimal residual myeloma cells, post treatment
It uses adopted EuroFlow guidelines and Cytognos software
It has a sensitivity of 10(-5) or better, depending on the antigenic profile of abnormal plasma cells
Reflex Test :