REF MISC

N-Methylhistamine, 24 Hour Urine

Synonyms:
Histamine metabolites
N METHYL U
Performing Lab:
Referral Laboratory
Patient Preparation:

Patient must not be taking monoamine oxidase inhibitors (MAOIs) or aminoguanidine as these medications increase N-methylhistamine levels.

Container Type:
Plastic transport tube
Specimen Type:

24 hour urine collection (no preservative). Alternately, a pour-off sample from a 24 hour urine collection is acceptable but client must measure 24 hour urine volume and indicate the amount on the requisition.

Preferred Volume:
5 mL from a 24 hour collection
Minimum Volume:
3.0 mL
Collection Procedure:

24 Hour Urine Collections:
1. To begin collection, empty the bladder and discard this urine. Record this time and date as the start of the collection.
2. 24 hour urine collections should be started Sunday through Thursday.
3. Collect all urine excreted during the next 24 hours in the urine collection container.
4. Exactly 24 hours after the collection was begun, empty the bladder for the last time. Add this urine to the 24 hour urine container. The collection is finished.
5. The container should be refrigerated during and after the 24 hour collection period until it can be brought to Saint Luke’s Regional Laboratories.

Store and Transport:
Refrigerated
Stability:

Room temperature - 28 days
Refrigerated - 28 days
Frozen - 28 days

CPT Codes:

82542 - N-methylhistamine, urine
81050 - Urine timed measurement

Method:
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS), Enzymatic Colorimetric Assay

Lab Personnel

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